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Spring 2020 – Predicting Transport Properties in Solid Tumors using General Algebraic Formulas

Affiliations:
BIMS Research Certificate Program
Project Leader: Madison Gray
madison_gray@tamu.edu
Biomedical Sciences Program
Faculty Mentor: Dr. Christopher Quick, Ph.D.
Meeting Times:
Thursday 9:35-10:50
Team Size:
4 (Team Full)
Open Spots: 0
Special Opportunities:
Mathematical Modeling
Description:
Experimental approaches to determine the flow of nutrients into tumors and the accumulation of fluid pressure in tumors are limited because they arise from the complex interactions of microvascular filtration into tumors and lymph flow from tumors. Existing mathematical models assume specific parameter values to solve, making results impossible to generalize. Therefore, the present work derived general algebraic formulas for critical tumor variables assuming the standard Starling-Landis and the Drake-Laine equations. This novel approach provides novel insights into how tumor properties can affect the transport of nutrients to the tumor and the high tissue fluid pressure within the tumor.

Written by:
Jennie Lamb
Published on:
February 18, 2020

Categories: FullTags: Spring 2020

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