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Spring 2018 – Algebraic Formula Predicting Preload Recruitable Stroke Work from Cardiac End-Diastolic and End-Systolic Pressure-Volume Relationships

Affiliations:
Project Leader: Lindsey Dekowski
v00116540@tamu.edu
Biomedical Sciences
Faculty Mentor: Dr. Christopher Quick Ph.D.
Meeting Times:
T/Tr 2:30-4:00
Team Size:
3 (Team Full)
Open Spots: 0
Special Opportunities:
Opportunities would include the ability to work with Dr. Quick, as well as potentially earn co-authorship on our manuscript pending publication, as well as become a full member of the team.
Team Needs:
Some understanding of Preload Recruitable Stroke Work (PRSW) as well as an understanding of our current manuscript/work would be preferential. We would also like someone with the ability to work in a group, and devote outside time to do individual research for the project.
Description:
The present work presents an algebraic formula for the relationship that predicts cardiac strike work as a function of end-diastolic diameter. The slope (i.e., preload recruitable stroke work, PRSW) was shown to be determined primarily by mean arterial pressure. Thus, PRSW can be highly influenced by systemic resistance, and may not be a reliable index of cardiac contractility. We are studying the reasons why it is not a reliable index.

Written by:
Jennie Lamb
Published on:
February 7, 2020

Categories: FullTags: Spring 2018

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