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Spring 2016 – Mapping genetic causes of differential diet response

Affiliations:
Project Leader: Bill Barrington
barrington@medicine.tamhsc.edu
Faculty Mentor: David Threadgill, Ph.D.
Meeting Times:
Summer 2016 (complete)
Team Size:
2 (Team Full)
Open Spots: 0
Special Opportunities:
Team Needs:
Previous laboratory experience is not required, and all science-related majors are invited to apply. Candidates must be willing to work with mice and take the required mouse handling trainings.
Description:
Previous research in our lab has shown that individuals’ response to diet is dependent upon their genetic background. Two genetically diverse mouse strains show opposite physiological responses to a high fat, high carbohydrate Western diet and a high fat, low carbohydrate ketogenic diet. We have generated an F2 cross between the strains. By measuring metabolic syndrome phenotypes in these individuals, we can map the genetic factors influencing response to diet. The team will be involved in mouse handling and phenotyping of metabolic syndrome traits. Ultimately, this will allow for a better understanding of the genetic factors controlling diet response in humans.

Written by:
Jennie Lamb
Published on:
February 1, 2020

Categories: FullTags: Spring 2016

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