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Fall 2024: Conserved deletions in ultra-conserved regions of mammalian genomes

Affiliations: Genetics & Genomics Research Leadership
Project Leader: Nicole Foley, Ph.D.
nfoley@cvm.tamu.edu
Veterinary Integrative Biosciences
Faculty Mentor: Bill Murphy, Ph.D.
Meeting Times:
Thursday 4-5pm
Team Size:
4
Open Spots: 0
Special Opportunities:
Depending on the outcome of the project, there may be an opportunity to publish the teams results. Students also have the option to participate in local conferences and meetings to disseminate their results
Team Needs:
Students will be trained in the bioinformatic skills needed to complete the project
Description:
The team will be trained to use bioinformatic methods to find conserved deletions in alignments of ultra-conserved regions of 241 mammal genomes. One identified, the team will validate the deletions using publicly available genome resources. And will use BLAT and the UCSC genome browser to determine if these deletions correspond to genes, if they are expressed, overlie regulatory elements etc.. Literature searches will be used to try determine the phenotypic outcomes of conserved deletions, providing insights into mammalian adaptation.

Written by:
América Soto-Arzat
Published on:
September 17, 2024

Categories: FullTags: Fall 2024

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