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Fall 2019 – Bioactivity Testing of Chemical Libraries to Identify Drug Candidates for Human Diseases

Affiliations:
Project Leader: Dr. Dwight Baker, Ph.D.
dwight.baker@tamu.edu
Biochemistry and Biophysics
Faculty Mentor: Dr. Inna Krieger, Ph.D.
Meeting Times:
Weekly TBD
Team Size:
6 (Team Full)
Open Spots: 0
Special Opportunities:
Students should register for 491 research credits. All team members will get valuable experience that would be desirable in industrial research laboratories and/or graduate research programs.
Team Needs:
The project can accommodate between 3 and 5 students that are detail-oriented and self-motivated to explore an important area of medical research. Students with some background in one or more of the following fields will be helpful, but not required: biological systems, human cell culture, microbiology, robotic instrument programing, inorganic chemistry, computer-based data entry and analysis, data visualization.
Description:
Drug discovery occurs in the modern scientific laboratory by screening libraries of chemicals in model biological or biochemical assays to identify those compounds which interact with the disease target. Team members of this project will participate in all aspects of the drug discovery process from development of one or more hypotheses, conceptualization of new or re-formatted assays, continuing through the hands-on performance of the assay using automated instruments, analysis and visualization of data through a web-based cheminformatics database, and presentation of results in a scientific forum. The laboratory is currently working on human diseases like tuberculosis, malaria and numerous types of cancer.

Written by:
Jennie Lamb
Published on:
February 12, 2020

Categories: FullTags: Fall 2019

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