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Fall 2018 – Ascitegenic Gains: Identifying the Primary Mechanical Determinants of Ascites Fluid Formation

Affiliations:
Project Leader: Nicholas Tan
nicholas_tan@tamu.edu
Biomedical Sciences
Faculty Mentor: Dr. Christopher M. Quick, Ph.D.
Meeting Times:
W 3:00 – 3:50, F 9:10 – 10:00
Team Size:
4 (Team Full)
Open Spots: 0
Special Opportunities:
Co-authorship is available to those who have significant contribution to the project. Conference presentation opportunities are also available.
Team Needs:
We are particularly interested in undergraduates who possess proficient technical writing skills and basic familiarity with biological systems. Basic understanding of physiology (or willingness to learn such from us) is a requirement. All majors are encouraged to apply. All undergraduates required to be enroll in 3 credit hours of VTPP/BMEN 291 or 491.
Description:
Ascites, the accumulation of fluid in the abdominal cavity, is the result of an imbalance in the inflow and outflow of abdominal fluid . The objective of this project is to algebraically model “ascitegenic gain” – the sensitivity of fluid accumulation with respect to changes in fluid parameters such as capillary pressure. Previous numerical models of the disease state are complex and overly reliant on extant parameter values. The algebraic nature of our work defines the relationships between fluid parameters rather than calculating their discrete values – proving particularly useful in guiding further ascites research.

Written by:
Jennie Lamb
Published on:
February 9, 2020

Categories: FullTags: Fall 2018

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