Nutrients absorbed into the interstitial space from the intestinal lumen can be transported either by intestinal capillaries to the liver or by the mesenteric lymphatics to the great veins of the neck. Several factors can alter the fraction of nutrients and fluid that is transported by mesenteric lymphatics, including abnormal liver function. The purpose of the present work is to develop a simple algebraic formula that predicts the fraction of nutrients and fluid that is transported by the mesenteric lymphatic vessels. This model will not only allow for the prediction of nutrient transport, but will also serve as a novel tool in characterizing critical parameter values in clinically relevant disease states. Currently the project is in the writing phase, however, interpreting previous data, validation, and exploring disease states are also major focuses.
| Affiliations: | |
| Project Leader: | Chesley Johnson cmjcmj25@tamu.edu Veterinary Physiology & Pharmacology |
| Faculty Mentor: | Christopher Quick, Ph.D. |
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Meeting Times:
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Th 12:45PM-2:00PM |
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Team Size:
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3 (Team Full) |
| Open Spots: | 0 |
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Special Opportunities:
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This project is well-developed, with a manuscript in preparation for submission. Team members will have the opportunity to earn co-authorship. |
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Team Needs:
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We are looking for team members that can use their skills to advance the project to a completed manuscript. We are particularly interested in students that have strong writing ability. An additional requirement we have is the ability to synthesize information from multiple scientific journals. Lastly, the project being a mathematical model, we are interested in students that have a mathematical modeling background. |
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Description:
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Nutrients absorbed into the interstitial space from the intestinal lumen can be transported either by intestinal capillaries to the liver or by the mesenteric lymphatics to the great veins of the neck. Several factors can alter the fraction of nutrients and fluid that is transported by mesenteric lymphatics, including abnormal liver function. The purpose of the present work is to develop a simple algebraic formula that predicts the fraction of nutrients and fluid that is transported by the mesenteric lymphatic vessels. This model will not only allow for the prediction of nutrient transport, but will also serve as a novel tool in characterizing critical parameter values in clinically relevant disease states. Currently the project is in the writing phase, however, interpreting previous data, validation, and exploring disease states are also major focuses.
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