| Affiliations: | |
| Project Leader: | Anson Harris anson_harris@tamu.edu Veterinary Physiology & Pharmacology |
| Faculty Mentor: | Christopher Quick Ph.D. |
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Meeting Times:
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TBD based on team member availability |
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Team Size:
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4 (Team Full) |
| Open Spots: | 0 |
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Special Opportunities:
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Possibility of a conference presentation, with significant contributors having their name on any created abstracts as well as be listed as co-authors. This project will also allow for the development of lab and research skills. |
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Team Needs:
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Willingness to work with chicken embryos Ability to work independently in a group setting Flexible schedule All undergrads required to enroll in VTPP 291/491 (3 credit hour research) |
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Description:
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The chick chorioallantoic membrane (CAM) is an excellent model to study the structure and function of development of the fetal heart and vasculature, given rapidity of growth, cost, and ease of use. Although the CAM model can be studied in situ (inside of the shell), investigators have prefered growing the chick ex-ovo (outside of the shell) to provide easy access for serial study of the same vessels of the microvascular network over the course of multiple days. However, the ex-ovo CAM model has not been optimized for chronic microvascular studies, which requires access for intravital microscopy, prevention of infection, and control of environmental humidity and temperature. The purpose of this project is therefore to develop a novel microvascular ex-ovo cam model that is robust, easy to implement, inexpensive, and amenable to become the basis of a large-scale resource for the new Certificate Program in Biomedical Research.
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