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Fall 2023: Mechanisms of sterility in gene drive mice to develop population suppression tools.

Affiliations: Genetics & Genomics Research Leadership
Project Leader: Ana Velasquez
avelasquez1086@tamu.edu
Molecular and Cellular Medicine
Faculty Mentor: David Threadgill, Ph.D
Meeting Times:
TBA
Team Size:
4
Open Spots: 0
Special Opportunities:
Students will have the chance to participate in local research conferences such as the Texas Genetics Society Conference. Students that wish to participate in the summer may continue in a paid position depending on performance and demand for undergraduate assistance.
Team Needs:
Interest in conservation and genetics.
I am looking for motivated students that are eager to learn and are willing to commit and communicate.
Students will learn methods in molecular biology, bioinformatics, and laboratory animal use. For this reason, previous basic knowledge of biology and/or genetics is preferred.
Must be willing to spend some time engaging in scientific literature.
In particular (but not exclusively), I’m looking for 1-2 students with interest in computation and bioinformatics to analyze RNAseq data
Description:
Invasive mice populations on islands are a big threat to the Earth’s biodiversity. Current population control methods are risky. The overall goal of my project is to develop a mouse line that can only have male progeny (i.e. a daughterless mouse). I work with a specific strain of mice (tw2) that carry an allele that makes males sterile when homozygous. Undergrads will help me conduct experiments and analyze data to better understand the mechanisms and genes responsible for this sterility phenotype.

Written by:
Christopher Quick
Published on:
August 22, 2023

Categories: FullTags: Fall 2023

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