| Affiliations: | STEM Research Leadership |
| Project Leader: | Mariam Othman Mariam.othman@tamu.edu Health & Kinesiology |
| Faculty Mentor: | John Lawler, Ph.D. |
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Meeting Times:
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TBD |
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Team Size:
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8
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| Open Spots: | 0 |
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Special Opportunities:
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Potential opportunities include co-authorship on multiple peer-reviews journals, conference presentations, opportunities to co-lead webinars for national organizations, and ongoing mentorship from me
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Team Needs:
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I am looking for individuals who are enthusiastic about research and are willing to learn and grow alongside me. You do not need prior research experience, and I will support you throughout this research journey. I just ask that you are dedicated to this work, aspire to learn more about research, and are committed to this project. |
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Description:
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Mobility and production of mechanical force and power are vital to survival in most mammalian species. Skeletal muscles adapt their protein turnover and fiber cross-sectional area in response to changes in mechanical loading, energy, and nutrient sensing. Conversely, mechanical unloading that occurs due to bed rest, limb casting, splinting, or spaceflight results in rapid atrophy of skeletal muscles. While skeletal muscle remodeling in response to dynamic changes in mechanical stressors is conserved across mammalian species, the underlying cell signaling remains unresolved. Using a variety of molecular, cellular, and proteomic techniques Our lab focuses on pro-inflammatory signaling, oxidative stress, and reduced stress response to mitigate skeletal muscle atrophy |