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Spring 2022: Direct Detection of Overexpressed HIV-Associated miRNA Using Hybrid Nanoparticles

Affiliations: DeBakey Executive Research Leadership Program
Project Leader: Angela Michelle San Juan
angelasanjuan08@tamu.edu
Biomedical Engineering
Faculty Mentor: Samuel Mabbott, Ph.D.
Meeting Times:
TBA
Team Size:
3
Open Spots: 0
Special Opportunities:
attending conferences, earning co-authorship , becoming full member of research group, prepare for R&D position for industry, networking opportunity.
Team Needs:
basic laboratory skills such as pipetting, centrifuging and weighing. These can be taught as well. Software skills with Solidworks/Fusion 360 is a plus. 3D printing is an additional plus.
Description:
This project mainly involves modifying nanoparticle surface with oligonucleotide probes that specifically detect upregulated HIV miRNA. miR-150 is a miRNA upregulated when a patient is infected with HIV. Early detection remains as a pivotal step in reducing the virus’s transmission and mortality rates especially in under-resourced populations where gaining access to clinical testing facilities can be difficult. The project mainly involves modifying nanoparticles with probes that can specifically and sensitively detect miR-150 and using SERS to precisely detect target HIV of interest.

Written by:
Christopher Quick
Published on:
January 22, 2022

Categories: FullTags: Spring 2022

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