| Affiliations: | Neuroscience Research Leadership |
| Project Leader: | Cassandra Kaufhold casskaufhold18@tamu.edu Neuroscience and Experimental Therapeutics |
| Faculty Mentor: | Dr. Farida Sohrabji & Dr. Rahul Srinivasan |
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Meeting Times:
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Mondays 1-2PM; can be flexible with time, not day |
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Team Size:
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3
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| Open Spots: | 0 |
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Special Opportunities:
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Consistent hard-work and dedication to a project has the potential for you to earn co-authorship on publications |
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Team Needs:
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Absolute requirement: Willing to work with rats and rat tissue collection (brain/gut). You will need to get a Rat handling certificate from CMP. My lab is located at the Health Science Center, therefore, it is HIGHLY recommended you have a TAMU parking pass (all TAMU parking passes work at the HSC). Otherwise, you would need to rely on bus schedules, which will involve travel time. Looking for highly self-motivated freshman or sophomores that are willing to work either early mornings afternoons/late afternoons |
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Description:
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Under the co-mentorship of Dr. Sohrabji and Dr. Srinivasan, I am currently investigating the extent to which gut pathology temporally correlates with the progression of PD and VP. There is growing evidence that manipulating the microbiome is beneficial in animal models of PD, however, we do not yet understand how and what specific gut pathologies correlate with distinct PD- and VP- related behaviors. I hypothesize that PD and VP models will have different gut pathology profiles that follow disease progression. To answer this hypothesis, I plan to use 6-OHDA to mimic PD related behaviors and inject ET-1 into the DLS to mimic VP related behaviors. I envision that the findings from this study will eventually contribute to therapeutic development via manipulation of the gut |