| Affiliations: | |
| Project Leader: | Chanyanuch Nakapakorn cnakapakorn@tamu.edu Biomedical Sciences |
| Faculty Mentor: |
Dr. Christopher M. Quick, Ph.D.
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Meeting Times:
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Monday 9:10 – 10AM
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Team Size:
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4 (Team Full)
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| Open Spots: | 0 |
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Special Opportunities:
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Team members have opportunities to earn 491 research credit for Fall 2018, earn co-authorship of manuscript to be published in a peer review journal, and gain scientific writing experience.
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Team Needs:
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No prior research experience required; proficiency in mathematical software mathematica; interests in biomedical science research
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Description:
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The liver is surrounded by a layer of connective tissues called the Glisson’s capsule. The Glisson’s capsule has been observed in experiments to adapt in permeability under certain conditions and may play a role in the regulation of ascites, excess fluid collected in the peritoneal cavity. Therefore, the purpose of the present work was to incorporate capsular adaptation into a hepatic fluid balance model to quantify its role in mediating lymph flow and ameliorating ascites formation. Algebraic model characterizing hepatic fluid balance with capsular adaptation has been constructed. The team is currently working on a manuscript to further describe the interactions of important hepatic parameters and the primary mechanical determinants of fluid volume regulation as well as the possible applications of the model.
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